Disease burden refers to the impact of a health condition on an individual or population in terms of mortality, morbidity, disability, and financial costs. It encompasses the overall impact of a disease or condition on the quality of life and functioning of individuals, as well as the economic and societal costs associated with its treatment and management. Research in the area of disease burden seeks to quantify and understand the impact of various diseases on populations, including the number of cases, severity of illness, and the resulting years of life lost or lived with disability. This information is used to inform public health policies, healthcare resource allocation, and research priorities to effectively reduce the burden of diseases and improve overall population health.